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The CA 15-3 assay value, regardless of level, should not be interpreted as absolute evidence for the presence or absence of malignant disease. The CA 15-3 assay value should be used in conjunction with information available from clinical evaluation and diagnostic procedure.

The CA 15-3 test is only useful when it is positive.  Often it is not.

References Hayes DF, Zurawski VR Jr, and Kufe DW, "Comparison of Circulating CA 15-3 and Carcinoembryonic Antigen Levels in Patients With Breast Cancer, J Clin Oncol, 1986, 4(10):1542-50.


Normal Range: Less than 32 U/mL.


Values obtained with different assay methods should not be used interchangeably.

CA 15-3 Breast Tumor Marker